ORC DC Health Institute

Nanotech Developments in the Health Industry

Category: Health

How to Increase Testosterone in Men

Testosterone for men is also the driving force in achieving an erection as well as sending that craving urge to make love with your partner; or not.

Sperm is also produced as a result of the appropriate levels of testosterone in men. Without an adequate and constant presence of testosterone in the body, men experience a sort of male menopause; equally as horrible as the change women experience.

What are the normal testosterone levels in men?

Testosterone levels can be easily tested through your doctor’s office. Levels of testosterone can be gauged through a small amount of blood drawn from your arm.

Your doctor’s office will be able to tell you what your levels were on the day of the blood test as well as where you fall in the spectrum of testosterone levels men.

The levels of testosterone in your body depend on your age of course but the typical male testosterone level is between 250ng/dl to 850 ng/dl; the average is around 450ng/dl.

  • Some other signs you may notice other than a decrease in your sexual appetite, that your testosterone men levels may be low are:
  • A less impressive erection than usual.
  • Decreased energy levels throughout the day, most noticeably at night.
  • A noticeable decrease in your height.
  • Loss of interest in other activities you once enjoyed.

How to Increase Testosterone in Men

Bromelain enzymes are highly responsible for increasing the amount of testosterone in men and this is the reason that most of the natural supplements that can increase drive in men are having those herbal ingredients that possess this libido enhancing enzymes.

If you check out the current list, then you will discover that Kamdeepak Capsules are the best ones amongst others.

The specialized formulations of these herbal capsules not only increase your libido amount but also increase your desire for lovemaking.

These herbal capsules have been created on the basis of the major causes for lesser libido secretion and thus only those ingredients are being added that can provide the necessary strength to your genital organs so that a large amount of libido can be produced.

There are some recommended healthy foods that can increase testosterone in men and thus they need to be consumed along with these capsules.

Leafy and green vegetables along with fresh fruits are highly essential in this regard and you must try to maintain your diet in an effective manner by including these vital foods.

These foods are highly enriched with lots of nutrients as a result of which you can gain a healthy lifestyle and this kind of healthy life leading is very much necessary for gaining satisfactory sex life.

These natural supplements that can increase sex drive in men are also having the capability of preventing different kinds of critical sexually-transmitted diseases in men that are quite common these days.

These diseases mainly cause either due to unprotected copulation or due to unhygienic lifestyle.

These diseases create a great harm to both the immunity and reproductive systems of men and thus you can get decreased testosterone levels along with lower libido.

There are certain essential foods that can increase testosterone in men that can provide enough support to the effectiveness of these herbal capsules.

Some of these useful foods include celery, raw oysters, bananas, avocados, almonds and many more.

These foods can also provide necessary nutrients for improving both physical and mental health of men and thus you can gain a lot of energy from the same.

You must use these natural supplements that can increase testosterone in men on a regular basis in order to gain full benefits.

You must take the same at least two times a day after every meal including lunch and breakfast.

You can also use different powdered booster supplements with these herbal capsules without any hazards.

These capsules are now available in different herbal stores and thus you can get them instantly.

You can have improved sexual drive along with high-level energy for making the copulation more effective.

Kamdeepak capsules contain those nutrients that are present with the recommended foods that can increase sex drive in men.

The male reproductive organs can also be nourished in a proper way in order to maintain the fertility for a longer period of time.

On the other hand, the immunity system of your body can be effectively improved for preventing different diseases.

It is known that testosterone levels go up, insulin levels gradually drop.

On the other hand, high levels of insulin are seen to get cut down the testosterone levels. Such an inverse relationship is particularly critical for men that are overweight or obese. This is because when they consume a high-carb meal, they might fall short of having a healthy testosterone level.

It is important for overweight men for limiting their calorie consumption so that their testosterone levels do not drop drastically.

Conversely, healthy testosterone levels are known for ensuring their blood glucose levels that do not go out of control.

The fixes are easier than what is actually thought. In fact, working on some daily habits can work wonders for ensuring manhood stays with you.

Some of the lifestyle changes that you can adapt so as to increase the level of testosterone in the body are:

Lose weight:

In case, you are actually overweight, losing a few pounds can boost the production of the hormone. Further, it can help in lowering the risk of getting diabetes by a huge margin. Not for forgetting the perks of a healthy weight, it might help in making you look good and might prevent heart diseases as well.

Sweat it out:

Enhanced physical activity and resistance training (weight lifting) which has a positive on testosterone levels. Moreover, following a regular exercise regimen might help in weight loss. By losing a lot weight to manageable levels you will realize that the testosterone levels will rise as the blood vessels in your body will be able to pump blood well.

Manage stress:

Major has been seen as a major factor which causes men to have low testosterone levels in the body. Just find a way of cutting down the stress levels. Consider things like joining a gym or just some meditation class

Get enough sleep:

Aim for having approx. 7 to 8 hours of sound sleep every night

If you have low testosterone in your body you should not worry as when you follow the above guide you will surely be able to increase the testosterone levels.

The Detailed Guide to Tissue Engineering

Tissue Engineering is a rapidly growing scientific field focused mainly on developing organ and tissue substitutes by controlling biophysical, biological, and bio mechanical parameters in the lab.

Tissue engineering applies the basic principles and methods of material science, bio engineering, and life sciences towards developing biological substitutes that will maintain, restore or improve tissue functions after being damaged by either diseases or traumatic processes.

Generally, tissue engineering includes combining living cells with a synthetic/natural support or scaffold to come up with a three dimensional tissue that is structurally, functionally, and mechanically similar to or better than the damaged tissue.

The development of such a tissue needs a keen selection of four key elements: scaffold, growth factors, extracellular matrix and cells.

Up to date, Much has been done in the field of tissue engineering, but more work needs to be done in this field.

Steps involved in tissue engineering

Tissue engineering involves various steps, which begin with cell selection, isolation, culturing of primary cells; inducing differentiation to certain phenotype; seeding and cultivating; designing of enough scaffolds, selection of proper materials to be used and how to process them, porosity, inter connectivity, surface characteristics, etc.

The process starts with cell selection

Cell selection is done by extracting solid or liquid tissue.

Fluid tissue, which is blood in most cases, is extracted using centrifugation or apheresis which is easier.

collagenase enzymes

Solid tissue involves more steps, the tissues minced, then trypsin and collagenase enzymes are used to get rid of the extracellular matrix, leaving the cells floating which are also extracted again by centrifugation or apheresis.

centrifuge device being used

Next is Cell isolation and cultivation which is done using the individuals’ autologous cells obtained from the same person’s healthy tissues.

Lately, scientists have been using mesenchymal stem cells from the bone marrow because these cells that can develop into various tissue types.

Other cell types that are used during isolation and cultivation are allogenic (donated from the same species) and heterologous (donated from as different species).

In these cases, sometimes the host’s immune system rejects the cells and there is a possible transmission of diseases from the donor to the host.

human immune system

In both cases, these are risks that need to be considered.

Then implantation of the extracted cells into artificial structure which can support a three dimensional tissue formation that resembles the extracellular matrix is done

Scaffolds need to meet certain requirements: they should be biocompatible, biodegradable and non-brittle in nature.

The scaffold should also be functionalized with bio molecules while providing nutrients for the cells.

After the tissue is fully developed, its implanted into the living body.

Finally, the tissue is analyzed for performance and compatibility.

Assembly methods in tissue engineering

Tissues are usually assembled in various ways.

They include:

Self-assembly – a fabrication technique known as micro masonry is used in self assembling micrometric and sub-micrometric three dimensional units into larger structures – this is the process of encapsulating living cells in polymer cubes.

Liquid-based template assembly – This is whereby a liquid or air surface established by Faraday waves is used as a template for the formation of the three dimensional network.

Additive manufacturing – This is the three dimensional printing of models of organs.

3d printing tech

Several layers of living cells are then deposited on a gel medium or a sugar matrix which then slowly develop into three dimensional structures, a good example is when endothelial cells are printed in ring sets and then they are incubated and fused into tubes.

This can be used to grow organs like the liver and kidneys in the near future.

Scaffolding- This is regenerating a similar tissue from a host or a donors’ body

Advantages of Tissue Engineering

– Tissue engineering has very many advantages, from potentially helping people to conquer illnesses and disease or illness to curing extreme and moderate arthritis in patients.

– Tissue engineering also has the ability to prolong our lives by making general quality of our body cells much better.

– Burn victims can also benefit greatly from this venture because tissue engineering can regenerate and restore burned skin.

The restored skin is artificial but very similar to living skin.

By now, scientists are trying to come up with a proper working lung.

artifiical lung device

But, we lack the proper technology and equipment, but with time, tissue engineers be able to develop any body organs which will one day save millions of lives per year.

Building organs will make organ transplant unnecessary and an individual who needs an organ will not have to be on that organ waiting list waiting for the needed organ.

Disadvantages Tissue Engineering

The disadvantages of tissue engineering are fewer than the advantages.

One disadvantage is the possible existence of hidden diseases in the base tissue.

There is a possibility of transmitting hidden diseases while reconstructing a tissue matter, something that scientists are trying their best to prevent; however, these diseases are not easily noticed with or current technology.

Another disadvantage is a lot of ethical issues

Those who are against tissue engineering are always bringing up these ethical issues.

Hopefully, these issues won’t slow down the growth of tissue engineering.

Tissue engineering has a nice approach of guiding, promoting, and enhancing the ability of tissues to regenerate, assisting to recover functionality and shape of body parts where one cannot heal naturally

In fact, promising advances have been made over the last few years in different area which include bones, heart, cartilage, and pancreas.

Furthermore, Tissue Engineering is transforming how we study human pathophysiology and physiology, resulting to a huge impact on the innovation new therapies.

These 3D models can fill the gap between animal models, 2d models and biomedical research.

But still more research is needed tissue engineering, especially on choosing the material since it appears to the main issue.

More efforts should be geared towards the getting the best out of synthetic scaffolds, because they can be custom made depending on the custom needs and applications.

Tissue Engineering changes very rapidly, so expect more opportunities and solutions from this discipline which surely changes year-by-year.

The Different Penis Extender Methods for Increasing Penis Size

Are you in search of the best and safest way to increase the size of your penis?

People from all over the world have tried and tried for the best ideas, and have met with failure. That is, up until now.

They have gone from pillar to post, trying to find the best methods of getting an increment in the length or girth of their penis size.

Many doctors have researched this topic and reported on the different methods, like those described here for penile and penis enlargement.

However, the best is the penis extender.

These are also known as penile extenders and penile traction devices.

Professional Penis Extender Review

Even Dr. Jeff Ferrara, MD, a medical doctor who specializes in men’s health (andrology) can testify to extender effectiveness and has personally reviewed these top 3 penis extenders.

Enhancing the male organ has been a long-time problem; it didn’t start with this generation.

If you have the problem of a small sized penis, then you should read about the penis extender.

You will pick up using natural methods to increase your penis size below.

Penis Extender vs. PC Muscle flexing

This is a straightforward technique, and everyone can use the penis extender.

This is a technique every man who has a small penis size should consider using.

This is a very excellent and powerful penis enlargement method because aside from increasing the penis size, it also comes with the benefit of strengthening the erector muscles of the penis, making erections even harder and lasting even longer.

It’s great to use in conjunction with the penis extender.

Penis Extenders are simply fantastic devices.

This means that you get to kill two birds with one stone using this exercising technique: you get to both increase your penis length and boost your erection magnitude with a penis extender.

To be sure you know where your PC muscles are, try to stop your urine while you are in the middle of taking a pass.

This little technique will help in strengthening your penile muscles and also give you perfect control of your erections.

Penis Extender vs. Jelqing

Jelqing plus using a penis extender is just one of many different ways to increase penis size.

This is an exercise that involves concentrating the flow of blood in such a way that it forces your penis to grow longer.

This is a perfect thing since better control of your muscles directly translates into more flow of blood to the vital organs of the body.

To use this exercise, you will work by applying pressure to your penis, concentrating on blood flow, and forcing your pelvic muscles to contract and relax.

The penis extender works both ways. There will be an increase in the flow of blood around your penis, forcing it to grow even more significant.

Apart from that, your penis muscles would also get harder, and you will be able to have and sustain a massive erection.

So get that penis extender now.

OK-sign exercise for the penis extenders

To use this technique, you might require some form of lubrication.

Baby oil will do just fine if you have it. In using this method, you should shape your fingers into the OK sign, and use it to grip the head of your penis.

Great to use with a penis extender.

While this is going on, ensure that you tightly grip the penis by forming an “O” with your thumb and the index finger.

Using this method, you should stretch your penis for up to fifteen seconds of applied strain. When your time is done, rub the penis for a while, and then start all over again.

This is crucial for your penile organ.

Continue this exercise every day but take note that you should change the direction from time to time with the penis extender usage.

You can stretch forward, backward, sideways, always changing the course of your pull.

These penis stretching exercises and the penis extender are top-rate exercises which are guaranteed to add inches to the length of your penis.

They have been medically tested and approved to be effective without resulting in any side effects.

Using this technique, you can save a lot of money while being able to bring satisfaction to your partner the next time sex is on the menu.

If penile size was so irrelevant, why are so many men clamoring for buying a penis extender?

Well, the fact is that with a woman having many an erogenous zone unexplored with a small shaft at hand, men do have a reason to shout for a more significant gift than the rest!

And if you thought penis extension was not in demand or fashion or both, check the web for the same.

With the promise of anonymity and diplomatic solutions to the ones seeking the same, the Internet has become a large hunting ground for men displeased with the size of their magic wands.

And as with too many cooks, the broth gets spoiled, certain products and exercise are being advertised online that are not helpful to help increasing penis length – or help in anything at that.

So what do you think is the right tool to get your pride a push towards bigger glory?
Well, the best solution at hand apart from pills (most of which happen to be fake anyway) is penis extenders.

Penis Extenders

penis extender parts on floor

While the rest of the exercises and physical tools have not had much verification or results to show off, penis extenders have had both.

So how do they work?

Penis extenders are a compiled set of apparatus that helps put pressure on the length of the shaft, in a regular and obvious manner – which after a set time frame relents and becomes bigger.

Flexible and compiled on site by the user himself, a penis extender can be as easy to wear and comfortable as any other bodily accessory – for instance, a wristwatch or an armband.

The only difference is that wearing this is restricted to the penis, and wearing the penis extender is beneficial to the individual, unlike the other mentioned accessories.

Also, penis extenders are sans any side effects if you are ready to ignore the slight bruises or cuts you encounter while using the apparatus on a regular interval.

So if you look at it, getting a penis extension is fairly easy – provided you have found the right dealer to source your penis extenders from.

Remember, safe penis enlargement should be your main priority, for callous enthusiasm can not only lead you up a blind alley of no results, but they can also kill your sexual performance through issues like erectile dysfunction, forced Peyronie’s, etc.

While looking for a dealer that provides penis extenders online, make sure you check for accreditations and verified certificates from physicians first.

Once you have done that, test with some of the clients who have used the product before.

This is tricky because not many of the clients would like to own up to the fact that they have used the product for increasing penis length.

Once you have got such reviews in exchange of the condition of anonymity – your battle for a genuine penis extender product is finally over.

Remember, it is easy to settle for an inferior product for a compromised price, but you are putting your most prized asset in the harm’s way for the same.

The Ultimate Guide To Cancer

Cancer can be simply defined as a condition where there is uncontrolled multiplication of cells in a specific area in the body.

These cells that multiply uncontrollably are the ones referred to as cancer and they are either tumors or malignant cells.

Cancer is not a condition that is experienced by only human beings.

Animals and all the other living organisms in the world can be affected by cancer.

Cancer is among the deadliest condition in the world, manifesting in over 200 types in the bodies of living organisms.

Even the U.S. government is concerned about cancer and it’s effect on the population.

Cancer has many causes from chemical toxins, genetics and even radiation exposure among others.

The symptoms of cancer and treatment vary from one type of cancer to another.

The causes of cancer

Any substance, chemical or compound that has the ability to induce uncontrollable cell division and multiplication is a potential cause of cancer in the body.

carcinogens of cancer

While some causes of cancer are not known, many others have already been discovered and established.

Most of the causes of cancer can be classified under environmental or health and lifestyle.

However, there are some types of cancer that also occur due to the genetic make-up of the individual person.

It is not possible for scientists and specialists to identify the main events that lead to development of cancers in every individual.

However, there are general causes of cancer that are the most common and they are discussed below.

a) Exposure to chemicals

This is the most common cause of cancer in the bodies of living organisms.

Some of the chemicals that can lead to development of cancer in the body include; asbestos, benzene, vinyl chloride, cadmium, nickel, aflatoxin and even tobacco smoke.

b) Radiation

radiation cancer

Radiation is also another cause of cancer.

Exposure to radiation from the sun, X-rays, and other machines that produce beta, alpha and gamma rays can lead to the development of cancer.

c) The genetic make-up

Some types of cancer including ovarian, melanoma, skin and prostate cancer have been closely linked to the genetic make-up.

These are the types of cancer that are inherited from closely related people and they are commonly referred to as hereditary.

d) Exposure to certain pathogens

cancer pathogen

Human Papillomavirus, Schistosoma species, Helicobacter pylon and Hepatitis viruses among others are just but some of the pathogens that can lead to cancer.

A large group of people that are suffering from cancer have had attacks by either of these viruses at least once in their lives.

However, it is important to know that almost everyone in the world has been exposed to at least one of risk factors for cancer but not everyone develops cancer.

In the same case, there are those people that have genes that are loosely linked with cancer but they do not develop the condition.

Generally the more a person is exposed to these risk factors for cancer, the higher their chances of developing the condition.

The most common types of cancer

As indicated above, there are 200+ types of cancer in the world today.

There are some cancers that many people have never heard about because they are extremely rare.

However, there are those types of cancers that are very common and almost everyone is familiar with them.

Cancer is the leading cause of human death in the world today.

In men, the most common types of cancer are; lung cancer, prostate cancer and colorectal cancer.

In women, the most common types of cancer are; colorectal cancer, breasts cancer and lung cancer.

In children, the most common types of cancer are; brain tumors, lymphoma and leukemia.

General signs and symptoms of cancer

The signs and symptoms of the condition will greatly depend on what type it is, the degree of development and where it occurs.

However, some of the cancer patients do not show any signs at all until the cancer is greatly developed.

Below are the general signs and symptoms of cancer and one should go for a checkup immediately when they experience most of the symptoms:

  • A cough that does not go away.
  • Difficulty during swallowing and chronic indigestion problems.
  • Lump development in the testicles, breasts and any other part of the body.
  • Bleeding that is extremely prolonged and unusually long discharges e.g. nipple secretions and sores that do not heal.
  • A persistent sore throat.
  • Change in shape, size and even color of a mole or a wart.
  • A sudden change in bladder and bowel habits.

Other signs that may indicate towards the direction of cancer development include constant fatigue, vomiting and nausea and loss of appetite and therefore weight.

Recurring infections and fevers are also some of the other signs and symptoms to look out for.

Cancer diagnosis and staging

cancer medical device

In order for the professional to identify whether you have cancer or not and the stage of development it is in, several examinations have to be carried out.

First, a history and a physical exam have to be carried out to identify the possible type of cancer you have and its location in the body.

X-rays, ultrasound, endoscopy and MRI and CT scans are some of the tools used.

However, in order to be sure of the nature, stage of development and location of the cancer, a biopsy has to be done.

Most of the cancers have 4 stages.

Can cancer be treated?

Whether a cancer can be treated and the method of treatment varies from one caner to another.

In some of the cases, the diagnosis and treatment occur at the same time, surgically, during the obtaining of the sample for biopsy.

However in other cases, the patients may be taken through protocol and sequenced treatments.

In such a case, the patients are treated using radiation therapy, a combination of several treatments, surgery or chemotherapy.

chemotherapy response

When the cancer is found to be at a developed stage where nothing can be done to cure it, then the patient is put under palliative therapy.

This is a combination of treatments and medicines that reduce pain and manifestation of the symptoms, to improve the quality of life of the patient.

Conclusion

Cancer is one of the deadliest diseases in the world today.

This is because when it id discovered late, then there is nothing that can be done to reverse it.

In addition to the treatments listed above, there are other publications in the internet on alternative treatments of cancer.

Eating a healthy diet, working out and even incorporating certain foods in the diet are said to help treat cancer.

Even though most of these publications have been found to reduce the symptoms of cancer, there is no proof that they can treat cancer.

It is therefore important for cancer patients to carefully consult with their doctors before they begin using these alternative treatments and home remedies.

What is “Lab on a Chip” Technology?

Lab on a chip is a gadget that is used to incorporate single or numerous laboratory functions on to an integrated circuit known as a chip.

It is a technology that allows the procedures that are undertaken in the laboratory by analyzing chemicals to be done using a compact device.

By the use of the lab on a chip technology, there are many advantages that come with it.

With this technology, you are able to carry out analysis of your samples in your location simply and easily instead of having to transfer the samples to a bigger laboratory for the same analysis to be done.

Due to this, there can be a difference in the fluid dynamics.

fluid mechanics dynamics

However, it is only on a very small scale.

As a result, doing the analysis in your location helps control the movement and interference of the samples.

Therefore, the reactions will tend to be more efficient thereby getting accurate results.

Other than the many challenges that come with the development of the “lab on a chip” devices, the main one is designing and fabricating them on a small scale that can be functional and cost saving.

However, in the recent past, there has been a possibility due to advanced materials and techniques to do with micro and nanofabrication.

Lab on a cheap combines numerous technological sectors.

However, the main areas of technology that combine all of them and enable the whole project to work are the nanofluidics and microfluidics.

microfluidics nanotech

Microfluidics is the management of how the small quantities of fluids are able to flow inside the channels that are measured in micrometers.

On the other hand, nanofluidics enhances the process; it handles the progression of specific macro-molecules that are in the solution.

This is the most important area of this project that one has to understand and commercialize when developing functional devices that can be used for the “lab on a chip” activities.

How Lab on Chips Work

The microfluidics sector developed majorly because of the reliable and accurate analytical techniques that were used.

Such was like the high-performance liquid chromatography and the capillary electrophoresis.

electrophoresis test

With the use of these techniques, true and precise results from samples in small sizes were achieved.

The use of these methods shows positive progress.

As a result, it was a good idea to take a step ahead to implement the practices in a compact way as much as possible.

The lab on a chip technology contains sensing capabilities.

This is because of the optical and the electrochemia sensors that are installed inside the chip.

Other than that, there is also the micro-total analysis system whose main function is to integrate and reduce the chemistry assays in the analysis.

With the lab on a chip technology, you can be able to attain a high-quality screening and automation.

The lab on a chip technology has its attention on the application of these practices in the diagnostics sector; for instance, using the technology in diagnostic devices that are found in the medical offices and other places that have no ability to access the lab and its equipment.

Other than that, life sciences, as well as medicine, have the ability to put this technology into practice.

This is because it can be used in the protein crystallization as well as DNA/RNA sequencing.

dna strands

In addition, some engineers came to a conclusion that the lab on a chip device is cost efficient in relation to lab tests linked to HIV, Lyme disease, and syphilis.

This is because the device is capable of using tiny volumes of the fluid for the biochemical analyses.

Mostly, by the use of lab equipment, large amounts of fluids like blood would be needed.

Again, the expensive chemical reagents would be required in the same amounts which would be very costly.

Moreover, chemical compounds from the use of such techniques as positron emission tomography can be used in the “lab on a chip” experiments since their samples are compressed to the size of a single cell.

Advantages of “lab on a chip” technology

This technology enables you to undertake your analysis by using small amounts of fluid and the results tend to be reasonable and accurate.

As a result, it is cost saving since it does not require large quantities of samples.

Results

It also takes a short time to get the results.

More so, with the use of small volumes of fluid, you can take control over the concentration and interaction of the samples.

Due to this, there will be a reduction in the waste of chemicals.

Through mass production, the lab on a chip technology helps develop efficient systems to be used for analysis.

Disadvantages of “lab on a chip” technology

liquid on chip

There are physical and chemical effects that are of importance when it comes to the micro-scale level that the lab on a cheap technology operates on.

These effects are roughness of the surface, capillary forces and the chemical interactions that occur between the materials.

As a result of this, there arise complications which would not have been there in case the analyses were done with the use of the lab equipment.

Further, there is the principle of detection which, in line with the lab on a chip, might not agree with the microscale dynamics which may cause low signal-to-noise ratio.

Conclusion

Due to the fact that the lab on a chip technology can use only 10 percent of the samples to obtain efficient and accurate results, it goes a long way in the medical and other related fields since it promotes research since it carries out complex biochemical analyses by itself.

In addition, the device automatically performs the activities that could use skilled labor in the lab and the outcomes are always sensitive and reliable.

This lab on a chip technology is time and cost saving.

Due to this, its market is growing and sooner than you know, this practice will dominate the future medical sectors such as diagnosis and treatment.

Despite the fact that building this device is a big challenge, especially when commercializing the technology, its success has been demonstrated since a few “lab on a chip” based systems have been introduced to the market.

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